TD is a potentially irreversible neurological disorder caused by long-term dopamine receptor blockade. If a patient on long-term therapy develops signs of TD, the primary step in treatment is to discontinue metoclopramide as soon as clinically feasible.
Metoclopramide Akathisia Management Strategies and Treatment
Akathisia, a feeling of inner restlessness and an inability to sit still, and parkinsonism, with symptoms like tremor and rigidity, are other key EPS manifestations. It can also affect the limbs, causing choreiform movements that resemble fidgeting or dancing.
Headaches and dizziness may also occur. Treatment for established TD is challenging and may involve medications like VMAT2 inhibitors (valbenazine, deutetrabenazine) to help manage the involuntary movements.
Metoclopramide Akathisia Management Strategies and Treatment
Managing EPS is a clear example of why metoclopramide side effects treatment requires close medical oversight. The most frequently reported issues are related to the drug's dopamine-blocking action in the brain, which can mimic symptoms of Parkinson's disease.
More About Metoclopramide side effects treatment
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