While symptoms may partially reverse over time, they can sometimes persist, making early detection and intervention critical. Akathisia, a feeling of inner restlessness and an inability to sit still, and parkinsonism, with symptoms like tremor and rigidity, are other key EPS manifestations.
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Acute dystonia, characterized by sudden, painful muscle contractions often affecting the neck, eyes, or jaw, is a prominent example. Common Side Effects and Initial Management Most individuals taking metoclopramide will experience some common, generally mild side effects.
It can also affect the limbs, causing choreiform movements that resemble fidgeting or dancing. Gastrointestinal symptoms like diarrhea or constipation, while counterintuitive for a gastric motility drug, are also seen.
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Headaches and dizziness may also occur. Long-Term Risks and Tardive Dyskinesia Perhaps the most serious concern with metoclopramide is the risk of developing tardive dyskinesia (TD) with prolonged use.
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