While this "Berlin Method" is not scalable due to its high risk and complexity, it provided definitive proof that a cure is possible. These reservoirs are scattered throughout the body, including the gut, brain, and lymphoid tissues.
Steroid Concept HIV Cure Strategy: How 'Shock and Kill' Could Target Hidden Reservoirs
Instead, a combination of approaches tailored to different individuals is the most probable outcome. While a singular, universally accessible cure remains elusive, the landscape of 2024 is defined by unprecedented momentum.
"Shock and kill" strategies are at the forefront of research, aiming to reactivate the dormant virus (shock) so the immune system or new drugs can eliminate it (kill). By suppressing the virus to undetectable levels, ART prevents disease progression and eliminates the risk of sexual transmission, a concept known as U=U (Undetectable = Untraceable).
Steroid Concept as a Potential HIV Cure Strategy
Broadly Neutralizing Antibodies (bNAbs) One of the most exciting developments involves broadly neutralizing antibodies (bNAbs). Gene editing tools like CRISPR-Cas9 are being refined to cut out HIV DNA from the genome.
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