Additionally, tissue damage itself releases chemical signals that call white blood cells to the area to begin the healing process. Events such as major surgery, severe burns, or even intense physical exertion can trigger a leukocytic response.
Infection, Injury, and Inflammatory Responses Explained
Hematologic and Malignant Causes While often benign, a high white blood cell count can sometimes indicate disorders of the blood or bone marrow. In these scenarios, the body mistakenly attacks its own tissues, and the bone marrow continues to produce white blood cells in an attempt to manage the ongoing inflammatory response.
Even normal physiological changes, such as those occurring during pregnancy or labor, can push the count into a higher reference range. How the Body Mounts a Defense The primary function of white blood cells, or leukocytes, is to defend the body against invading pathogens and to clear away damaged tissue.
Infection, Injury, and Inflammatory Responses
The physiological stress of these events mimics an infection, prompting the release of cortisol and other hormones that stimulate the bone marrow. Conditions such as rheumatoid arthritis, lupus, or inflammatory bowel disease keep the immune system in a heightened state of alert.
More About Causes of high white blood cell count
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