The body attempts to wall off the damage by laying down collagen, leading to the formation of scar tissue, or fibrosis. These particles are so small—typically less than 10 micrometers in diameter, and often much smaller—that they evade the natural defense mechanisms of the respiratory system.
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When materials containing silica, such as quartz, are disturbed by cutting, grinding, drilling, or blasting, they release microscopic particles into the air. The Immune System’s Fatal Response While the immune system attempts to phagocytize these silica particles, the silica itself is toxic to the macrophages.
Specific Occupational and Environmental Causes The specific environments that create the conditions for this disease are varied but share a common thread: high concentrations of airborne silica dust. Sandblasting, which propels abrasive silica sand at high pressure to clean or etch surfaces.
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The causes are not limited to one sector, but rather span industries where stone, rock, or sand are manipulated. Construction, particularly cutting or grinding concrete, brick, or stone countertops.
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