These drugs block calcium from entering the cells of the heart and arterial walls, which decreases muscle contraction and widens blood vessels. Grapefruit juice can interfere with the metabolism of certain calcium channel blockers, leading to higher levels of the drug in the blood and an increased risk of side effects.
Serious Risks of Calcium Channel Blockers Explained
Drug Interactions and Contraindications Side effects of calcium channel blockers can be exacerbated when combined with other substances. Nausea or mild stomach discomfort in some sensitive individuals.
Flushing or a feeling of warmth is caused by the widening of blood vessels in the skin. Non-dihydropyridine calcium channel blockers, such as diltiazem and verapamil, affect the heart's electrical conduction more significantly.
Serious Risks of Calcium Channel Blockers: Side Effects and Safety Concerns
Additionally, combining these medications with beta-blockers can significantly slow the heart rate. Heart Rate and Fatigue Some individuals experience a slower heart rate (bradycardia), which can lead to feelings of fatigue or weakness.
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