Regardless of which side you personally choose, the key to recruiting Serana is to declare that you will "join him, but not as a vampire. Once you deliver the Black Soul Gem to Harkon, he will perform the ritual, stripping you of your humanity and solidifying your new bond with his daughter, Serana, who will then be available as a follower.
Fixing Serana Follower Bugs in Skyrim
If you fail to make this choice and simply attack Harkon immediately, the opportunity to gain Serana as a follower in this manner is lost, locking you out of this particular recruitment method for the remainder of the playthrough. The journey begins at Castle Volkihar, the iconic vampire stronghold floating in the sky.
Serana remains a vital character in the world and can still be recruited. By defeating the undead guardians and freeing her from her prison, you can initiate a personal quest where she will ask to join you, effectively allowing you to recruit her as a follower at a later stage.
Fixing Serana Follower Bugs in Skyrim
This location is a hidden realm accessible only through a Falmer teleportation circle, which you must locate and activate. This method requires more exploration but offers a second chance to add her to your party.
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